United Kingdom Prospective Diabetes Study (UKPDS)

doctor checking blood pressure

UKPDS shows Type 2 diabetes is progressive.

The study also showed that high blood glucose and high blood pressure both play an important role in the development of diabetes complications.

The UKPDS showed that long-term complications of type 2 diabetes can be prevented through intensive blood glucose and blood pressure management: The UKPDS included almost 4,000 people with newly diagnosed type 2 diabetes.

The study demonstrated that:

  • Type 2 diabetes is progressive over time, and as the pancreas loses its ability to make insulin, more treatment is required
  • High blood glucose and high blood pressure both play an important role in the development of diabetes complications.

Intensive blood glucose control & management of hypertension resulted in fewer diabetes related complications, and approximately

  • 20% decrease in death related to diabetes
  • 40% decrease in eye, kidney, and nerve diabetes complications
  • 40% decrease in blockage of the blood vessels to the lower limbs
  • 15% decrease in heart attack

For every 10 mmHG drop in the systolic blood pressure, there was approximate 12% decrease in:

  • Death related to diabetes
  • Eye, kidney, and nerve diabetes complications
  • Heart attack

©2007-2017 Collective work Martha Nolte Kennedy,
The Regents of the University of California.
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