Ketones & Insulin Pumps

woman with insulin pump

Check for ketones if you have the following:

  • An unexplained elevation in your blood sugar
  • Persistently elevated blood sugars
  • Symptoms of nausea or vomiting

There is a higher risk for developing ketones on pump therapy. This is because long-acting insulins are not used, and rapid-acting insulin is delivered in extremely small amounts. If this basal insulin delivery is interrupted for more than an hour, check your blood sugar and ketones. If you continue to not get insulin, blood glucose and ketone levels may increase into a dangerous range. See also Acute: Diabetic ketoacidosis (DKA).

Insulin pump-related ketone buildup may be caused by:

  • Infusion set problem (See Tips on infusion sets and sites)
  • Site problem
  • Air in tubing (resulting in missed insulin)
  • Extended pump suspension or disconnection (for more than one to two hours)
  • Pump malfunction
  • Insulin leakage (at insertion site or infusion set connection site)
  • Illness or infection
  • Vomiting or dehydration
  • Severe emotional stress
  • “Spoiled” insulin

Ketones checklist

The presence of ketones while using an insulin pump can indicate a serious medical emergency.

Check for ketones if you have:

  • An unexplained elevation in your blood sugar
  • Persistently elevated blood sugars
  • Symptoms of nausea or vomiting

This is because you want to be sure you are not developing diabetic ketoacidosis. Remember that ketoacidosis occurs more commonly in pump users. Here’s what you should do. Use the mnemonic KISS.

K – Check for Ketones
I – Give Insulin by Injection (using an insulin pen or syringe – not through the pump)
S – Change the infusion Set
– Check blood Sugar

If ketones are positive, you need to obtain emergency medical care.

Treating ketones

If you have elevated ketones, insulin replacement must be delivered via an injection with an insulin pen or insulin syringe instead of the pump because the pump or infusion set may be malfunctioning and causing ketones to develop.

Remember! Ketoacidosis is a medical emergency that requires immediate medical attention. Always carry an insulin vial and syringe or an insulin pen with needle for backup. Speak with your doctor and have a backup plan in case of pump malfunction.

Self-assessment Quiz

Self assessment quizzes are available for topics covered in this website. To find out how much you have learned about  Insulin Pumps, take our self assessment quiz when you have completed this section.  The quiz is multiple choice. Please choose the single best answer to each question. At the end of the quiz, your score will display. If your score is over 70% correct, you are doing very well. If your score is less than 70%, you can return to this section and review the information.

©2007-2020 Collective work Martha Nolte Kennedy,
The Regents of the University of California.
All rights reserved.