Learn more about metformin
- Thiazolidinediones (glitazones):
Learn more about thiazolidinediones
- Insulin releasing pills (secretagogues):
Learn more about pills that cause insulin to be released from the pancreas
- Starch blockers:
Learn more about starch blockers
- Incretin based therapies:
Learn more about incretin based therapies
- Amylin analogs:
Learn more about Amylin analogs
- SFUs, repaglinide and nateglinide can cause hypoglycemia. The risk of hypoglycemia is increased when meals are skipped. Avoid skipping meals.
- “Clinical” maximum daily dose for glyburide is 10 mg and glipizide is 20 mg; higher doses are not likely to further lower the blood glucose.
- These medicines do not cause hypoglycemia when used alone. However, when used with SFUs, repaglinide, nateglinide, or insulin, hypoglycemia may occur.
- Lactic acidosis symptoms: feeling very weak, tired or uncomfortable; unusual muscle pain, trouble breathing, unusual or unexpected stomach discomfort, feeling cold, feeling dizzy or lightheaded, or suddenly developing a slow or irregular heartbeat.
- Radiologic tests using iodinated contrast media: stop metformin at the time of or prior to the procedure, and withhold for 48 hours after procedure and restart after kidney function has been re-evaluated and found to be normal.
- Liver toxicity symptoms: unexplained nausea, vomiting, stomach pain, unusual tiredness, loss of appetite, dark urine, or yellowing of the skin or whites of eyes.
Table is prepared with information from package inserts of the various medications and opinion of the UCSF Diabetes Teaching Center.
This table is not meant to be all inclusive and contains important educational information, as viewed by the UCSF Diabetes Teaching Center.
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